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Wosulin 50/50 Injection (40 IU/ml) is a premixed insulin formulation that contains 50% short-acting soluble insulin and 50% intermediate-acting isophane insulin. It is used to manage blood sugar levels in people with diabetes mellitus, especially when control with oral antidiabetic medications, diet, and exercise is inadequate.

Primary Uses

1. Type 1 Diabetes Mellitus:

   • Replaces insulin in individuals whose bodies do not produce any or enough insulin.

2. Type 2 Diabetes Mellitus:

   • Used when oral antidiabetic medications and lifestyle modifications are not sufficient to control blood sugar levels.
   • May be used as part of combination therapy with other antidiabetic agents.

3. Combination Insulin Therapy:

   • Provides both basal (background) and prandial (mealtime) glucose control in a single injection.

How It Works

• Soluble Insulin (50%):
  • Provides rapid-acting control of blood sugar levels during and immediately after meals.
  • Starts working within 30 minutes, peaks in 2-4 hours, and lasts about 6-8 hours.
• Isophane Insulin (50%):
  • Offers sustained release to manage blood sugar levels between meals and overnight.
  • Starts working in 1-2 hours, peaks at 4-12 hours, and lasts up to 24 hours.

Administration

• Injected subcutaneously (under the skin), typically 15-30 minutes before meals.
• Dosage and frequency depend on the individual’s blood sugar levels and doctor’s recommendations.
• May require adjustments based on blood glucose monitoring results.

Wosulin-R Injection (40 IU/ml) is a short-acting human insulin used to manage blood sugar levels in individuals with diabetes mellitus. It contains recombinant human insulin, which mimics the insulin naturally produced by the pancreas.

Primary Uses

1. Type 1 Diabetes Mellitus:

   • Replaces insulin in patients whose bodies do not produce it.

2. Type 2 Diabetes Mellitus:

   • Used when oral antidiabetic medications, diet, and exercise are insufficient to control blood sugar levels.

3. Management of Hyperglycemia:

   • Controls high blood sugar levels, preventing complications such as nerve damage, kidney problems, and eye issues.

4. Hospitalized or Surgical Patients:

   • Often used to manage blood sugar levels in patients undergoing surgery or in those with acute illnesses.

How It Works

• Short-Acting Insulin:
  • Starts working 30 minutes after injection.
  • Peaks in effect within 2-4 hours.
  • Duration of action is about 6-8 hours.
  • Regulates blood sugar levels by facilitating glucose uptake by cells and reducing glucose production by the liver.

Administration

• Injected subcutaneously (under the skin), typically 15-30 minutes before meals.
• Dosage is individualized based on blood sugar monitoring and doctor recommendations.
• Can be mixed with intermediate or long-acting insulin for a combination effect.

Wosulin 30/70 100 IU/ml Injection is a combination insulin preparation used for the management of diabetes mellitus. It contains two types of insulin: 30% regular insulin (short-acting) and 70% NPH insulin (intermediate-acting). This combination is designed to help manage blood glucose levels in individuals with diabetes, both for immediate and long-term control.

Primary Uses of Wosulin 30/70 100 IU/ml Injection:

1. Management of Type 1 Diabetes:

   • In Type 1 diabetes, where the body does not produce insulin, Wosulin 30/70 helps to control blood sugar levels. The combination of short-acting and intermediate-acting insulin provides both rapid and prolonged effects to regulate blood glucose levels after meals and throughout the day.

2. Management of Type 2 Diabetes:

   • Wosulin 30/70 is also used in Type 2 diabetes when oral medications (such as metformin or sulfonylureas) are not sufficient to control blood glucose. The insulin in this combination helps the body use glucose more effectively and maintain appropriate blood sugar levels.

3. Postprandial and Basal Control:

   • The short-acting insulin (regular insulin) in the formulation helps manage blood sugar spikes after meals, while the intermediate-acting insulin (NPH insulin) provides a longer duration of action to manage blood glucose levels during periods of fasting, such as overnight.

4. Insulin Therapy for Blood Glucose Control:

   • This injection is an important part of insulin therapy for individuals who need insulin replacement due to inadequate insulin production or effectiveness. It can be injected subcutaneously (under the skin) as part of a daily routine to manage blood sugar levels.

How Wosulin 30/70 Works:

• Regular insulin (30%) acts quickly to lower blood glucose after meals, typically within 30 minutes to 1 hour after injection.
• NPH insulin (70%) has a slower onset and a longer duration, which helps maintain more stable blood glucose levels throughout the day or night.

Dosage and Administration:

• Wosulin 30/70 is typically injected subcutaneously (under the skin) in areas like the abdomen or thigh. The dosage will be individualized based on the patient's blood glucose levels, insulin sensitivity, and overall treatment plan.
• Timing: It is often injected once or twice a day, usually before breakfast and dinner, but the exact timing and dosage depend on the doctor's recommendation.

Basalog 100 IU/ml Refill Cartridge contains insulin glargine, a long-acting insulin used to manage blood glucose levels in individuals with diabetes mellitus. Insulin glargine is a basal insulin, meaning it helps control blood sugar levels over an extended period, providing a steady, consistent level of insulin.

Main Uses of Basalog 100 IU/ml Refill Cartridge:1. Type 1 Diabetes:

• Basalog is used in the treatment of Type 1 diabetes (an autoimmune condition where the pancreas no longer produces insulin). In Type 1 diabetes, individuals must take insulin to manage blood glucose levels because their bodies can no longer produce it.
• Basalog provides a long-acting effect that helps control blood sugar levels between meals and overnight. It helps in basal insulin replacement, allowing the body to maintain stable glucose levels in the absence of the body's natural insulin production.

2. Type 2 Diabetes:

• In individuals with Type 2 diabetes, where the body either becomes resistant to insulin or does not produce enough, Basalog is used to help manage blood sugar. It can be used alongside other diabetes medications (such as oral hypoglycemics) to help control basal glucose levels and prevent spikes.
• It is often used in combination with short-acting insulin (for mealtime control) or oral diabetes medications.

3. Long-acting Insulin Therapy:

• Basalog 100 IU/ml is a long-acting insulin that provides 24-hour coverage. Unlike regular insulin, which acts quickly and has a shorter duration, Basalog helps to maintain stable glucose levels throughout the day and night without causing peaks or dips in blood sugar.
• This steady release of insulin is especially helpful for overnight glucose control and helps to manage fasting blood glucose levels.

4. Diabetes Management:

• Insulin glargine in Basalog helps to replace the insulin that a person’s body is unable to produce, allowing them to better manage their blood sugar levels throughout the day. It is a crucial part of the daily diabetes management regimen.

How It Works:

• Insulin glargine (the active ingredient in Basalog) is a long-acting insulin analog that works by slowly releasing insulin into the bloodstream over 24 hours, mimicking the body’s natural basal insulin production.
• It helps to regulate blood glucose levels by promoting the uptake of glucose into cells and preventing the liver from producing excess glucose.

Administration:

• The Basalog Refill Cartridge is typically used with an insulin pen (such as an insulin pen device) for convenient and accurate dosing.
• The insulin is injected subcutaneously (under the skin) once a day, at the same time each day. The dose and timing should be tailored to the individual’s needs and determined by a healthcare provider.

Side Effects:

• Hypoglycemia (low blood sugar): This is the most common side effect and can occur if too much insulin is taken, especially if meals are skipped or physical activity increases.
• Injection site reactions: Redness, swelling, or itching at the injection site may occur.
• Weight gain: Some individuals may experience weight gain while using insulin therapy.

Wosulin-N (40 IU/ml) is an intermediate-acting human insulin containing isophane insulin. It is primarily used to manage blood sugar levels in individuals with diabetes mellitus, including both type 1 and type 2 diabetes.

Primary Uses

1. Type 1 Diabetes Mellitus:

   • Replaces insulin in individuals whose bodies do not produce insulin.

2. Type 2 Diabetes Mellitus:

   • Used when oral antidiabetic medications, diet, and exercise are insufficient to control blood sugar levels.

3. Blood Sugar Regulation:

   • Provides a steady release of insulin to maintain glucose levels between meals and overnight.

4. Combination Therapy:

   • Often used in combination with short-acting or rapid-acting insulins for comprehensive blood sugar control.

How It Works

• Intermediate-Acting Insulin:
  • Begins to work within 1-2 hours after injection.
  • Peaks in effect at 4-12 hours.
  • Duration of action lasts up to 24 hours.
  • Helps maintain basal (background) blood sugar levels throughout the day and night.

Administration

• Administered subcutaneously (under the skin), usually once or twice daily, depending on the prescribed regimen.
• Dosage is tailored based on individual blood sugar monitoring and the doctor’s advice.
• Ensure injection site rotation (abdomen, thigh, or upper arm) to avoid skin issues.

Benefits

• Maintains baseline blood sugar control over an extended period.
• Reduces the need for frequent insulin injections.
• Can be part of a flexible insulin regimen when combined with short-acting insulin.